Any spurious blob on a symmetry axis is multiplied up of course.
And when you finish building side chains it may reduce in size. But waters etc can sit on special positions - you just enter them with occ = 0.5 and refine as usual.. Eleanor On 5 Nov 2012, at 09:49, Crystal Xu wrote: > Dear all, > I am now determining a structure at 2.2 A resolution. The space group is C2, > and there is only one molecular in an ASU. During the refinement, some weird > electron density appears right on the two-fold axis. Does anyone have any > idea what could this be? Thanks a lot. > > Best regards > > Shutong Xu
