Dear All,

We have a Post-Doctoral Research Associate position available within the UCL 
School of Pharmacy with an anticipated start date of February 1, 2013. It is 
currently advertised through jobs.ac.uk and UCL - reference 1298701. The post 
is for two years and funded by the IACR. We are looking for a candidate with 
hands-on knowledge of, biophysics, protein expression/purification, cloning and 
molecular biology techniques, experience in structural biology and some 
proficiency in X-ray crystallography.  If you have any queries regarding the 
vacancy please contact Dr G. Parkinson ( 
[email protected]<mailto:[email protected]> ) or if you have any 
queries regarding the application process, please contact Nadia Ali 
([email protected]<mailto:[email protected]>).

Details are provided below:

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Research Associate Position in the UCL School of Pharmacy - Laboratory of Dr 
Gary Parkinson. UCL Reference: 1298701.

Applicants are invited to apply for a Research Associate position in an IACR 
funded structure based drug discovery project aimed at characterising inhibitor 
binding sites that modulate protein dimerisation. The post is available from 
January 2013 and is funded for two years in the first instance.

The applicant will generate STAT3 proteins suitable for structural studies, set 
up appropriate crystallisations, collect and interpret the resulting 
crystallographic data. Subsequent structural interpretations will be used to 
validate and guide the design and synthesis of new effective small molecule 
ligands. The candidate is expected to work collaboratively, being involved in 
all aspects of the projects wider aims to understand factors controlling SH2 
dimerisation, STAT3 DNA binding and stability.

The successful candidate must have a Ph.D. in an area closely related to 
Structural Biology. Experience in structural biology is essential with a 
hands-on knowledge of, biophysics, protein expression/purification, cloning and 
molecular biology techniques.

A proficiency in X-ray crystallography and knowledge of macromolecular crystal 
growth are desirable.

Full time position. the appointment will be on UCL Grade 7. The salary range 
will be £32,055 - £38,744 per annum, inclusive of London Allowance.

If you have any queries regarding the vacancy please contact Dr G. Parkinson 
([email protected]<mailto:[email protected]>) or if you have any 
queries regarding the application process, please contact Nadia Ali 
([email protected]<mailto:[email protected]>).

Closing Date: 31 December 2012

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Sincerely,

Gary Parkinson
Dr Gary Parkinson
Room 216
UCL The School of Pharmacy
29/39 Brunswick Square
London WC1N 1AX  UK
tel (44) 0207 753 5933 fax (44) 0207 753 5933
email [email protected]<mailto:[email protected]>
http://www.ucl.ac.uk/pharmacy
http://www.ucl.ac.uk/pharmacy/people/StaffProfiles/parkison_g_profile<http://www.ucl.ac.uk/pharmacy/people/StaffProfiles/parkinson_g_profile>

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