Hi Abdul,

  The way in which I did it in the 2006 paper was a simple python script that 
selected the h+k+l = 2n or 2n+1 reflections from a plain text reflection list 
in the XDS format, wrote them out and and I then copied and pasted the header 
rows back in and used the resulting file as an input for XSCALE. However I 
think the separate scaling trick only works if you actually have a bimodal 
distribution of intensities and therefore the regular scaling algorithms  
overestimate the sigmas for the weak reflections. A way to check this is to 
look at the cumulative intensity distribution; if it looks normal I don't think 
the separate scaling will help you.

  HTH,
  Esko
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Esko Oksanen, PhD
Instrument Scientist - Neutron Macromolecular Crystallography

European Spallation Source ESS AB
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Century

On Dec 27, 2012, at 9:03 PM, Ethayathulla Abdulsamath wrote:

hi everybody

I have a question about scaling weak and strong reflections separately. I am 
working on P3 Pseudotranslation symmetry dataset with 0,0,0.5 translation. I 
have got soln through MR with in P3121, P3221, P321, with LLGs 1000, TFZ=15.2 
using phenix which has applied pseudotranslation and seems to be definite 
solution but i could not refine the structure the r-factor get struck with 
47/53. The molecule packing looks good with no space for another monomer. From 
the article 
Oksanen<http://scripts.iucr.org/cgi-bin/citedin?search_on=name&author_name=Oksanen%2C%20E%2E>,
 et al 2006 D62, 1369-1374 have scaled (h+k+l=2n+1) weak and strong reflections 
separately and used strong reflections for restrained refinement and weak 
reflections for rigid body refinement. I dont know how to scale them 
separately, so that i can try to refine the structure using weak and strong 
reflections. IF somebody can suggest how to scale them separately. I have also 
attached the hklview of reflections.


Thank you

Abdul

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