Postdoctoral Fellowship Opportunity Structure-based antigen engineering
Working in the laboratory of Dr. Tony Schryvers (University of Calgary), the postdoctoral scholar will spearhead protein engineering and structural studies to develop novel vaccine antigens. The ideal candidate will have expertise in protein crystallography and structural modeling and be within three years of receiving their PhD. In collaboration with Dr. Trevor Moraes (protein crystallography, University of Toronto) and Dr. David Schriemer (mass spectrometry, University of Calgary) the scholar will integrate these approaches to generate detailed models of interactions between native or engineered antigens and host proteins (antibodies and transferrin) and correlate these with functional activities such as complement activation, bacterial killing, or protection. These studies will enable us to probe the encouraging but unexpected findings from recent challenge experiments that potentially will lead to new concepts in vaccine design and development. The successful scholar will have ample opportunities for parallel professional development through courses, teaching or participating in various activities in the academic or industrial spheres depending upon interests. This position is funded by a University of Calgary program “Eyes High” which provides $50,000/a for two years. Applicants should provide a cover letter, CV, and contact information for three references to Carla Davidson, PhD, Project Manager AIHS Interdisciplinary Team on Vaccine Design and Implementation, [email protected]. Trevor F. Moraes (Ph.D.) Assistant Professor Canada Research Chair (Structural Biology of Membrane Proteins) Department of Biochemistry University of Toronto 1 King's College Circle Medical Sciences Building, Room 5366 Toronto, Ontario, Canada M5S 1A8 Email: [email protected] Phone: (416) 946-3048 Fax: (416) 946-8228 Web address: http://biochemistry.utoronto.ca/moraes/bch.html
