Posted on behalf of Prof. Daan van Aalten Dear all
I have two postdoctoral and one technical position(s) available in my research group, as listed below. Please apply through the mechanisms indicated although happy to discuss things informally via email. Candidates who in parallel are willing to apply for postdoctoral fellowships (e.g. EMBO/Marie Curie etc) are particularly encouraged to apply. best wishes Daan ########################################################################### Professor Daan van Aalten, FRSE Wellcome Trust Senior Fellow Division of Molecular Microbiology, College of Life Sciences University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, United Kingdom Tel/Fax: ++441382384979/8216 E-mail/WWW: http://davapc1.bioch.dundee.ac.uk The University of Dundee is a Scottish Registered Charity, No. SC015096 POSITION 1: Reference Number: LS0287 Job Title: Postdoctoral Research Assistant College: College of Life Sciences School: Life Sciences Research Division: MRC Protein Phosphorylation Unit Grade: Grade 7 (£29,541 - £36,298) Job Category: Research Closing Date: 15 February 2013 Subject Area: Molecular mechanisms of human signal transduction pathways A postdoc position is available immediately in the group of Prof. Daan van Aalten at the College of Life Sciences in Dundee, Scotland. You will be using X-ray crystallography to study the molecular mechanisms of a range of cellular processes linked to human disease. You will be working in a highly international research group that operates across the disciplines of cell biology, enzymology, drug design, structural biology and synthetic chemistry. More information on the group can be found onhttp://www.ppu.mrc.ac.uk/research/?pid=1007. Training, as required, will be provided in a well-equipped, well-funded and supportive environment enabling the successful candidate to extend skills and expertise. The College has excellent facilities for all aspects of research, including in-house and easily accessible services, such as cloning, proteomics, microscopy, DNA sequencing, oligo synthesis and preparation of growth media. The last model Rigaku X-ray generator with sample changer has just been installed and robotic crystallization will be available shortly. There is regular synchrotron access to Diamond/ESRF. This position is suited for a candidate with a PhD and postdoctoral experience in protein crystallography. The candidate should have several first author publications in good scientific journals. You will have extensive experience with a range of expression systems, purification techniques and all aspects of X-ray crystallography including experimental phasing. Work in the van Aalten lab is focused on the mechanisms by which post-translational modifications affect signalling processes in the brain (e.g. Nature Chemical Biology (2012), 8, 969-974), the innate immune system (e.g. EMBO J. (2012), 31, 1394-1404) and cancer (e.g. Science (2009), 326, 1707-1711). You will initiate a range of new collaborative projects and will be able to work independently and on several projects in parallel. The position is available immediately for a period of 24 months. The starting salary is a minimum of Grade 7, point 29 (£29,541). Tayside, one of the sunniest places in the UK, has a very affordable cost of living compared to places in the south of the UK, and countryside of outstanding beauty, including large sandy beaches and challenging hills. Information on moving and establishing yourself in Dundee as a postdoc is available from the College of Life Sciences Postdoc Association,http://postdoc.lifesci.dundee.ac.uk. Informal enquiries may be made to Daan van Aalten at dmfvanaal...@dundee.ac.uk. POSITION 2: Reference Number: (to be announced - check UoD HR website) Job Title: Postdoctoral Research Assistant College: College of Life Sciences School: Life Sciences Research Division: MRC Protein Phosphorylation Unit Grade: Grade 7 (£29,541 - £36,298) Job Category: Research Closing Date: 28 March 2013 Postdoctoral Research Appointment in X-ray crystallography Applications are invited for a postdoctoral position to work with Sir Philip Cohen and Professor Daan van Aalten funded by MRC Technology‘s Development Gap Fund. The successful candidate will work on a project to express, crystallize and solve the structures of pseudokinases that play key roles in innate immunity and are attractive targets for the development of anti-inflammatory drugs. Candidates applying for this position will have a obtained a PhD and have experience of using a range of protein expression and purification techniques and X-ray crystallographic studies to solve the structures of proteins linked to diseasee. You will be working with two highly international research groups that operates across the disciplines of cell biology, cell signalling, enzymology, drug design, structural biology and synthetic chemistry. More information on the participating groups can be found on http://www.ppu.mrc.ac.uk/research/?pid=1 and http://davapc1.bioch.dundee.ac.uk/new/index.html. The MRC PPU is one of the world’s leading centres studying the role of protein phosphorylation and ubiquitylation in cell regulation and human disease, is funded and equipped to the highest international standards, and its innovative collaboration with the pharmaceutical industry has won a Queen’s Anniversary Award for Higher Education The Unit is based within the College of Life Sciences at the University of Dundee, one of the top life science research institutes in Europe. In addition to an excellent scientific environment the Tayside region of Scotland offers an affordable standard of living in an area of outstanding natural beauty, being situated close to the sea. Large sandy beaches and the highlands of Scotland. The position is available immediately for an initial period of one year, but applicants wishing to start at any time until July 2013 will be considered. The appointment will be made at an appropriate point on the University’s Grade 7 (£29,541 - £36,298) salary scale depending on experience and achievements. Candidate requirements: • PhD with outstanding academic track record and at least one first authored publication in an internationally recognised peer-reviewed journal • Strong background in protein expression and X-ray crystallography. • Capable of working in a team, but able to plan and work independently • Excellent communication skills and knowledge of the English language are essential How to apply: To apply on-line please visit: www.dundee.ac.uk/jobs. If you are unable to apply on-line please contact Human Resources on (01382) 386209 (answering machine) for an application pack. Please quote reference number LS0269. Informal enquiries can be addressed to Daan van Aalten (dmfvanaal...@dundee.ac.uk) or Philip Cohen (p.co...@dundee.ac.uk). POSITION 3 Reference Number: LS0288 Job Title: Research Technician College: College of Life Sciences School: Life Sciences Research Division: Molecular Microbiology Grade: Grade 5 (£20,172 – £23,352) Job Category: Technical Closing Date: 22 February 2013 Subject Area: Molecular mechanisms of human disease A research technician position is available immediately in the group of Prof. Daan van Aalten at the College of Life Sciences in Dundee, Scotland. You will be using a range of protein expression and purification techniques to support X-ray crystallographic studies to unveil the molecular mechanisms of a range of cellular processes linked to human disease. You will be working in a highly international research group that operates across the disciplines of cell biology, enzymology, drug design, structural biology and synthetic chemistry. More information on the group can be found onhttp://davapc1.bioch.dundee.ac.uk/new/index.html. Training, as required, will be provided in a well-equipped, well-funded and supportive environment enabling the successful candidate to extend skills and expertise. The College has excellent facilities for all aspects of research, including in-house and easily accessible services, such as cloning, proteomics, microscopy, DNA sequencing, oligo synthesis and preparation of growth media. This position is suited for a candidate with extensive experience with a range of expression systems (i.e. bacterial, Pichia pastoris, mammalian cells, baculovirus) and purification techniques. You will have experience with running and maintaining Akta protein purification equipment. Excellent record keeping and communicative skills are essential and you will be interested in demonstrating techniques to new lab members. Work in the van Aalten lab is focused on the molecular mechanisms of disease processes linked to the brain (e.g. Nature Chemical Biology (2012), 8, 969-974), the innate immune system (e.g. EMBO J. (2012), 31, 1394-1404), cancer (e.g. Science (2009), 326, 1707-1711) and microbial infections (e.g. PLOS Pathog. (2012), 8, e1002373). You will support a range of new collaborative projects and will be able to work independently and on several projects in parallel. The position is available immediately for a period of 18 months. The starting salary is a minimum of Grade 5, point 16 (£20,172). Tayside, one of the sunniest places in the UK, has a very affordable cost of living compared to places in the south of the UK, and countryside of outstanding beauty, including large sandy beaches and challenging hills. Informal enquiries may be made to Daan van Aalten at dmfvanaal...@dundee.ac.uk. ########################################################################### Professor Daan van Aalten, FRSE Wellcome Trust Senior Fellow Division of Molecular Microbiology, College of Life Sciences University of Dundee, Dow Street, Dundee DD1 5EH, Scotland, United Kingdom Tel/Fax: ++441382384979/8216 E-mail/WWW: http://davapc1.bioch.dundee.ac.uk The University of Dundee is a Scottish Registered Charity, No. SC015096 -- Helge Dorfmueller flat 1/2 368 Perth Road DD2 1EN Dundee UK, Scotland
