I had a similar situation once where I intentionally collected 5-degree images from a salt crystal. I found this page:
http://strucbio.biologie.uni-konstanz.de/xdswiki/index.php/Small_molecules

most helpful. Particularly the "DELPHI" keyword. Thanks to Kay Diederichs for pointing this out to me.

-James Holton
MAD Scientist

On 3/13/2013 1:12 PM, Niu Tou wrote:
Dear colleagues,

We have some diffraction data from small peptide crystals, the shape of diffraction spots looks normal, and resolution is beyond 2A. The data were collected with 5 degree rotation per image. Later on we found it is hard to do index. Does anybody know some skills to figure this problem?

Best wishes,
Niu

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