Hi -

You can use Xia2

or, you can use Pointless ("Find or Match Laue group") to combine the two 
datasets after Mosflm in one  MTZ with common correct origin etc, 
and then use SCALA to scale them together.

For more info: 
http://ccp4wiki.org/~ccp4wiki/wiki/index.php?title=Data_processing_with_CCP4

Its btw the same procedures (albeit for a different problem) as suggested a 
week ago under the subject "Scaling with SCALA high and low resolution data 
sets"

A.


On Mar 28, 2013, at 11:08, S. Thiyagarajan wrote:

> Dear all
> I have two data sets, 75 frames each from crystals of the same protein - same 
> cell parameters/space group (P4).
> I could process them seperately each yielding > 90% completeness but with  
> poor multiplicity ( < 2 )
> 
> If I merge the data sets using CAD, I loose the data reduction statistics of 
> the combined data set.
> 
> I do not have HKL2000. 
> 
> Which (free) tool can handle two different diffraction data sets, process 
> them together to give a single final data statistics.
>  
> Thanks and regards
> Thiyaga
> 
> 
> 
> S. Thiyagarajan
> Centre of Excellence in Bioinformatics
> School of Biotechnology
> Madurai Kamaraj University
> Madurai - 625021
> Ph: +91-9159224881 (cell)

Anastassis (Tassos) Perrakis, Principal Investigator / Staff Member
Department of Biochemistry (B8)
Netherlands Cancer Institute, 
Dept. B8, 1066 CX Amsterdam, The Netherlands
Tel: +31 20 512 1951 Fax: +31 20 512 1954 Mobile / SMS: +31 6 28 597791





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