Hello everybody,
i am a freshman in structural biology. Right now i encountered two questions
and need help from all of you:
1) from the paper, i saw there are three different interactions between the
ligand and the residue:(i) hydrogen bonding, (ii) π–π stacking and (iii)
cation–π interactions, how can i determine which kind of interaction did happen
in my protein. i had chencked that there are no hydrogen bonds between the
ligand and the residue.
2) my protein is dimeric in the crystal, when i want to find the polar contacts
of one residue (pymol) and found that this residue has differnet polar contacts
in the two monomer. Is this acceptable?
Thanks in advance!
quanju
