Dear all,
I want to obtain a crystal structure of a ligand complex with my protein.
Unfortunately this ligand shows really limited solubility even in the
presence of up to 20 % DMSO and I would like some feedback about the use
of detergents to help with this matter.
Our idea is to use Triton X-100 to set up crystallization screens using
our Phoenix robot (Art Robbins Instruments).
Does anyone has experience with using detergent in general with this
equipment ?
Is there major issues, special cleaning procedures ?
Best,
Sebastien
