POSTDOCTORAL POSITION

KELCH LAB

UNIVERSITY OF MASSACHUSETTS, MEDICAL SCHOOL

Crystallographic studies of DNA replication machines



A postdoctoral position to understand the mechanism and structures of DNA
replication machines is available in the lab of Professor Brian Kelch at
the University of Massachusetts, Medical School in Worcester, MA. The Kelch
Lab merges structural, biochemical, biophysical and computational
approaches to dissect the mechanism of multi-protein assemblies involved in
DNA replication and DNA metabolism. More information is available at the
lab website:

http://labs.umassmed.edu/kelchlab/Lab_Website/Welcome.html



The position offers ideal opportunities for experienced crystallographers
interested in continuing structural studies, but who would like to
complement his or her expertise with other, diverse tools for understanding
the molecular basis for DNA replication and general ATPase mechanisms. The
fellow will benefit from both the multidisciplinary environment in the lab
and the highly collaborative UMMS community. The lab has extensive
crystallographic resources, including (as part of the UMMS crystallography
group) a new MicroMax-007-HF X-ray generator, a Saturn 944 HG CCD detector
and a Phenix crystallization robot.



Candidates should have (or expect) a Ph.D. or M.D. degree. Candidates with
experience in protein purification, crystallization, and structure
determination are strongly preferred. Applications will be reviewed as they
are received; start date is preferred by Fall 2013, but is negotiable.



Interested individuals should send a single PDF file containing their CV
along with a summary of previous research experience, accomplishments, and
expertise to Prof. Brian Kelch at:

[email protected]



Worcester is located less than 40 miles from Boston/Cambridge, and the area
has multiple career development opportunities for those interested in
careers in academia or industry. Moreover, the Worcester area is family
oriented, with numerous outdoor activities, some of the best public schools
in the nation, and a low cost of living.

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