Hi Shiva, There are some other enzyme systems activated by ligand induced oligomerization in addition to the ones on this list:
1) DNA polymerase dimerization on DNA binding 2) Restriction enzyme dimerization on DNA binding (an example is the type IIs FokI) 3) membrane enzyme receptors like receptor tyrosine kinase, etc. 4) metallopeptidases with dimerization domain Thanks, Debanu. -----Original Message----- From: CCP4 bulletin board [mailto:[email protected]] On Behalf Of Shiva Bhowmik Sent: Friday, August 09, 2013 10:19 AM To: [email protected] Subject: Re: [ccp4bb] Substrate/Ligand Induced Oligomerization of enzymes Dear All, Thank you for your responses. Below is the compiled list of examples of substrate/ligand/co-factor induced oligomerization: http://www.pnas.org/content/97/13/7096.full.pdf http://www.ncbi.nlm.nih.gov/pubmed/15710608 http://www.ncbi.nlm.nih.gov/pubmed/17725819 http://www.ncbi.nlm.nih.gov/pubmed/14724278 http://www.ncbi.nlm.nih.gov/pubmed/16338409 http://pubs.acs.org/doi/abs/10.1021/bi301067w http://pubs.acs.org/doi/abs/10.1021/bi2005637 http://pubs.acs.org/doi/abs/10.1021/bi201381e http://pubs.acs.org/doi/full/10.1021/bi301593c Have a great weekend. Cheers, Shiva On Thu, Aug 8, 2013 at 5:03 PM, Shiva Bhowmik <[email protected]> wrote: Dear All, I am looking for references and/or example of substrate or ligand induced oligomerization of enzymes related to activation. Any help in this regard would be greatly appreciated. Thanks. Shiva
