The early bird registration for the CCP4 study weekend closes tomorrow, 24th November.
After this date the registration fee increases and there will be no student bursaries available. For registration, please follow the link: https://eventbooking.stfc.ac.uk/login?EVENT=147 We cordially invite you to participate in the 2014 Study Weekend "Two Way Street - Complementary Methods". More than half of the deposited structures in the PDB are oligomeric, and about three quarters are annotated with ligands. This provides a strong motivation for the CCP4 users to understand what methods can be used to complement structure analysis and to learn how complementary techniques can be helpful in structure determination. The programme can be found at http://www.cse.scitech.ac.uk/events/CCP4_2014/programme.html You will learn how complementary methods help in structure determination and analysis, leading to a better understanding of the bio-macromolecules we study: * In-solution methods like SAXS or biophysical techniques allow validating the macromolecular assembly. * Biophysical techniques are also essential to probe ligands and co-factors. * We address how to make ligand complexes with novel methods to mount and manipulate crystals. * A session on drug design gives the perspective and discusses additional techniques such as NMR. * Simulations and NMR also address the dynamic nature of macromolecules. * EM techniques address macromolecular complexes and go full circle with the X-ray analysis. The organisers. Jon Cooper, UCL Ivo Tews, University of Southampton University of Southampton, Centre for Biological Sciences Institute for Life Sciences (IfLS) B85, Highfield Campus Southampton SO17 1BJ phone: ++44 (0)23-8059-4415 lab: -4365 fax: -5159 http://www.soton.ac.uk/sdc http://www.southampton.ac.uk/biosci/about/staff/it1y09.page?
