Dear Dhananjay,

I have been trying for more than one year to have a partial success with
Baculovirus!

Is not so straighforward, protein expression is a science by its own; so I
think there is not one or another universal protocol to try.

You need to have positive evidences in all the steps of the "production":
correct cloning, efficient transfection, titre of the virus, and play with
several parameters  (temperature, cultivation of cells in suspension or
monolayer, day of harvesting of the cells, protein extraction procedure).

Good luck!

Alberto Manfrin
ESR Marie Curie BIOMINTEC
University of Mainz
Germany
[email protected]


From:  dhananjay kulkarni <[email protected]>
Reply-To:  <[email protected]>
Date:  Sat, 7 Dec 2013 00:32:26 -0000
To:  <[email protected]>
Subject:  [ccp4bb] Insect cell SF9 expression

Dear all,
Does any one has protocols for expression and making stable virus for SF-9
Cell, I was trying 
with Invitrogen manual but somehow it is not working, any alternative
protocols which works
quickly? I am new to thins insect cell expression.
your suggestion and protocols are really helpful
Thanking in advance



Dhananjay.K
Post Doctoral Research Associate
Department of Biochemistry
Indian Institute of Science
Bangalore
India
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