Hi Richard,
I am not sure if this is what you are looking for: second order nonlinear
optical imaging of chiral crystals (SONICC). It is not based on a
computational algorithm but the nonlinear optical property of chiral
crystals to double the wavelength when illuminated by intense light.
Some recent publications:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264792/
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345893/
http://www.ncbi.nlm.nih.gov/pubmed/23765294
The instrument is also available on market.
Zhijie
-----Original Message-----
From: Richard Gillilan
Sent: Tuesday, February 04, 2014 10:10 AM
To: [email protected]
Subject: [ccp4bb] identifying protein crystals via visible light only?
Some years ago, I remember hearing about a microscope that used *visible*
light combined with some proprietary image processing algorithm to
distinguish between protein crystals, salt, and background. I can't remember
the company name or researchers involved.
Has anyone here heard of this?
Richard Gillilan
MacCHESS
Cornell
