Hi,

what was not mentioned in the ccp4 discussion is

The use of trimethylamine N-oxide as a primary
precipitating agent and related methylamine
osmolytes as cryoprotective agents for
macromolecular crystallography

Acta Cryst. (2012). D68, 69-81

I found it as a very potent compound for cryo-preservation of crystals.

Kind regards,
Reiner

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Dr. Reiner Kiefersauer
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