Dear all, I would like to announce this EMBO work-shop dedicated to protein-protein interactions with a large foccus on structural biology.
“Advances in protein-protein analysis and modulation”, 9-12 september 2014 in Hyères, France Application deadline: March 31 2014 Further information about how to apply, grants and fees can be found below and at http://events.embo.org/14-ppi/index.html Organizing comity : Xavier Morelli (FR), Francoise Ochsenbein (FR), Andrew Wilson (UK), Chandra Verma (SG), Stephane Betzi (FR) Confirmed speakers : Tom Blundell (UK); Cristina Cardoso (DE); David Fairlie (AU); Pierre Colas (FR) ; Christian Heinis (CH); Philippe Minard (FR); Michael Nilges (FR) Franca Fratarnali (UK); Ora Schueler-Furman (IL); Gianni Defabritiis (ES) Stefan Knapp (UK); Giovanna Zinzalla (SE) ; Nicolas Wolff (FR) ; Christian Ottmann (NL); Michele Arkin (USA) Anna Mapp (USA); Bruno Villoutreix (FR) Location : Presqu'ile de Giens. The EMBO Workshop will be hosted at the Club Belambra – Hyères, located in a secluded peninsula of the Mediterranean coast, on the French Riviera (south of France). Protein-Protein interactions (PPIs) play central role in the regulation of biological processes. After more than a decade spent struggling to discover what features of a protein are ‘druggable’, the modulation of protein–protein interactions (PPIs) has emerged from both academic and corporate research as a promising therapeutic strategy to treat human disease. As such, PPI modulators (PPIMs) are the next generation of highly innovative drugs that will reach the market in the next decade. The challenge now is to develop techniques, chemistry and knowhow required to rationally identify new targets and design potential PPI modifying compounds. This is very different from generating small molecules that target the catalytic sites of enzymes and will require different approaches in terms of chemistry, screening assays, in silico modeling and cellular techniques, not to mention the need of basic understanding of PPI biophysics. The EMBO Workshop aims to bring together experts from various fields who work on understanding and modulating PPIs and also to create a competitive European network. Topics: § PPI: New Targets / In Cells § PPI: Technological Advances / Methods § PPI analysis: Docking/Energetics/Prediction § PPPI modulation: Successful Examples § PPPI modulation: Chemical Biology / Chemoinformatics
