Dear all

A 4-year PhD studentship in Structural Biology starting October 2014 is 
available in the Research Group led by Dr Christian Siebold. Our group, based 
in the Division of Structural Biology (STRUBI) at the Wellcome Trust Centre for 
Human Genetics, University of Oxford is primarily focused on the structural 
biology of extracellular recognition and signalling complexes in development 
and cancer (https://www.strubi.ox.ac.uk/research/christian-siebold). STRUBI 
harbours a well-developed infrastructure for large-scale protein production, 
purification and crystallization with excellent access to the DIAMOND 
synchrotron and a range of biophysical and cell-based facilities.

The doctoral project concerns the structural and functional characterization of 
the Hedgehog and Bone Morphogenetic Protein signalling pathways. More details 
can be found under:
http://www.ndm.ox.ac.uk/doctoral-projects/project/structural-biology-of-cell-surface-morphogen-signalling

The studentship is funded by Cancer Research UK and applications are invited 
from recent graduates or final year undergraduates. Applicants should hold or 
expect to gain a first or upper second class honours degree. Cancer Research UK 
will pay a competitive salary (£19.000 p.a.) as well as University and College 
fees. Ideal candidates have a strong background in biochemistry and molecular 
or cell biology, but science graduates in general are welcome to apply. It 
would be an advantage, but is not necessary, for the candidate to have 
laboratory experience in any of the following: cloning, mutagenesis, protein 
expression, purification and crystallographic techniques. Candidates whose 
first language is not English will be asked to submit a certificate of 
proficiency in the English language (e.g. IELTS 7.5). 

Applications should be submitted by email to Sibel Ruc, HR Officer at 
[email protected]. Your application should consist of an up to date CV 
and supporting statement, which describes why in your opinion you would be the 
best candidate for the Cancer Research UK PhD Studentship. You should also 
provide full details of two referees and indicate whether they can be contacted 
at this stage. The closing date for applications is 25th April 2014.

For further information please contact Dr. Christian Siebold 
([email protected]).

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