Dear all, Applications are invited for an EPSRC CASE award in membrane protein crystallography and electron microscopy.
This PhD, funded by Pfizer Neusentis and an EPSRC CASE award, will use a multidisciplinary approach to study membrane ion channels important for human health and disease. This project will primarily be focused on X-ray crystallography and will take advantage of the recent £900,000 upgrade to the crystallization facility at the University of Leeds. In addition, single particle cryo electron microscopy will also be used, where appropriate, to obtain mechanistic information using new technologies developed at Leeds. The structural and mechanistic information obtained will lead into a structure based inhibitor design program. This project will allow the successful candidate to work in a multi-disciplinary field using cutting edge technologies. The demanding nature of this project means we are seeking highly motivated Ph.D candidates with an M.Sc./Bsc in biochemistry, molecular biology or a related discipline and a strong interest in structure-function studies on proteins. Experience of protein overexpression, purification, crystallization or membrane proteins is desirable but not essential. For informal enquiries and more details please contact Dr Stephen Muench ([email protected]), Dr Jonathan Lippiat ( [email protected] ) or Prof. Adrian Goldman ([email protected]). For applications please visit; https://studentservices.leeds.ac.uk/pls/banprod/bwskalog_uol.P_DispLoginNon Applicants must have an undergraduate- (minimum of 2:1, or equivalent) or masters-level degree in a related subject and must be UK or EU citizens (EU citizens must of resided within the UK for a minimum of 3 years to be eligible for the full stipend). The position will start in October 2014 and the closing date for applications will be 6th June. Best wishes, Stephen Dr Stephen Muench School of Biomedical Sciences University of Leeds Leeds LS2 9JT +44(0) 113 3434279
