Dear colleagues: We have a position available for an X-ray crystallographer. The job description follows. If you have any questions, please feel free to contact me.
Investigator III, Structural and Biophysical Chemistry About Novartis Institutes for Biomedical Research: At Novartis Institutes for BioMedical Research (NIBR), the global research organization of Novartis, we are committed to discovering innovative medicines to cure disease and improve human health. We aim to hire the best trained scientists from academia, biotechnology and pharmaceuticals and we cultivate an environment for drug discovery science where innovation is rewarded. It is ultimately the talent of the individuals we recruit that determines our success and our state-of-the-art technologies and resources that enable individuals to realize this success. NIBR has sites in Cambridge, Massachusetts; Emeryville, California; Basel, Switzerland; Horsham, UK; and Shanghai, China. Our Infectious Diseases research is headquartered in Emeryville, California under the global leadership of Don Ganem, M.D., one of the world's leading virologists and infectious disease specialists About Structural and Biophysical Chemistry Group: The NIBR Emeryville Structural and Biophysical Chemistry group is responsible for actively pursuing the structures of macromolecular drug targets either as apo-proteins or in complex with lead compounds to help guide structure-based drug design, and actively participates in the drug discovery process. The group also provides biophysics and solutions studies support for drug discovery projects. Position Description: The qualified candidate will use his/her scientific expertise to aid in structure-based drug design efforts. Specifically, this individual will determine high-resolution, three-dimensional structures of macromolecular drug targets (typically proteins), including crystallization and structure solution of medically important structures and target-ligand complexes. This individual will interact with computational chemists and medicinal chemists to design new scaffolds and improve lead compounds. Additionally, this individual will provide biophysical support for fragment based drug discovery efforts and other biophysical studies. Please apply at http://www.novartis.com/careers/job-search/#keyword=140884BR . referencing job ID 140884BR . You must apply on-line to be considered. Qualifications: The ideal candidate will have - * An M.S. degree and 7 or more years of work experience or a Ph.D. and 3-6 years of postdoctoral and/or work experience. Degrees in Biochemistry, Chemistry, or Molecular Biophysics are acceptable. * Strong experience in protein biochemistry, protein crystallization, crystallographic methods, structure solution, structure refinement and molecular modeling. Pharmaceutical industry experience is a plus, as is experience in membrane protein crystallography and experience in developing biologics. * Significant experience in the use of biophysics (SPR, ITC, DSC, NMR, etc.) to support biological research and drug discovery projects. Experience in supporting fragment-based drug discovery is a plus. * Excellent verbal and written communication skills and the ability to work in large, multidisciplinary project teams. The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. Our policies are not to discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status. Dirksen Bussiere, Ph.D., M.B.A. Director, Structural and Biophysical Chemistry Novartis Insts. for BioMedical Research 4560 Horton Street, M/S 4.6 Emeryville, CA 94608-2916 USA Phone +1 510923-2114 Fax +1 5106559910 [email protected]<mailto:[email protected]> www.novartis.com<http://www.novartis.com/>
