Please see below for a postdoctoral opportunity here in Manchester.

All enquiries should be made to [email protected]

Thanks

Colin



Postdoctoral Position in X-ray Crystallography

Structure of the endosomal ESCRT-I complexes

Faculty of Life Sciences, University of Manchester
Manchester, UK

A postdoctoral position is available in the laboratory of Dr Lydia Tabernero to 
study the structural basis for the assembly of a protein complex that is 
essential for mitogenic receptor down regulation. The project will focus on 
understanding the core structure of the endosomal-sorting complex, ESCRT-I 
(Stefani et al., 2011, Curr. Biol. 21, 1245050; Wunderley et al, 2014, J Cell 
Sci. 127, 663-72).
The position is part of an ongoing research collaboration between Dr Lydia 
Tabernero and Professor Philip Woodman directed towards understanding the 
molecular basis for the down-regulation of the epidermal growth factor 
receptor. This is a high-impact fast-moving basic research area with direct 
implications for bettering our understanding of a key cellular process that is 
disrupted in several diseases. The successful applicant will join a 
collaborative team, also involving the laboratories of Professor Philip Woodman 
and Dr Alan Roseman, and will use X-ray crystallography, and other structural 
techniques (EM, SAXS).
The ideal candidate will have a PhD in structural biology, and will have 
experience in recombinant protein expression and X-ray crystallography.
The post is full time for up to 15 months and can be available immediately.

Salary: £29,837

Closing date: 15/08/2014
Reference: LSX-04954
Further particulars and a full description of the project and job 
responsibilities can be found at: www.jobs.manchester.ac.uk
Informal enquiries
Informal enquiries can be made to Dr Lydia Tabernero, Lecturer:
Email: [email protected]
Telephone: 0161 275 7794
The University of Manchester values a diverse workforce and welcomes 
applications from all sections of the community.



Manchester
Protein
Structure
Facility

Dr. Colin W. Levy
MIB G034
Tel.  0161 275 5090
Mob.07786 197 554
[email protected]<mailto:[email protected]>

Reply via email to