Hi, The research group of Dr. Reza Khayat at the City College of New York (www.khayatlab.org) is seeking candidate postdoctoral fellows to study host pathogen interaction using a combination of cryo-electron microscopy (cryo- EM), X-ray crystallography, biophysics and biochemistry. The research group is particularly interested in elucidating the structural mechanism by which enveloped and nonenveloped viruses and bacteriophages interact with their hosts to: acquire cellular entry, hijack cellular machinery, disassemble, replicate, assemble and egress. The group is also interested in determining the mechanism by which host antibodies and synthetic DNA aptamers neutralize the viruses.
The group has dedicated access to a JEOL 2100 and Zeiss EM902 for grid preparation and screening, and to the resources at the New York Structural Biology Center (NYSBC) that include facilities for cryo-EM grid and sample preparation, JEOL 3200FSC, Tecnai F20, JEOL 2100F, JEOL 1230 and a FEI Helios 650. The group also has dedicated access to state-of-art instrumentation to be housed at the Advanced Science and Research Center (ASRC). Both NYSBC and ASRC are located in adjacent buildings and within five minute walking distance from the laboratory (GPS: 40.815927, -73.951201). The group has open access to multiple Gryphon LCP robots for conducting crystallization experiments at multiple temperatures, Alchemist DT for screen optimization, and Minstrel HT for crystal imaging and data storage. The group shares the following instrumentation: microplate readers, ITC, DLS, CD, and bioreactors. Candidates must have a Ph.D., be highly motivated, exhibit independence, and have experience with protein purification. Salary will be competitive for the NYC area and be commensurate with experience and prior success. Please send a cover letter, CV, and the names with contact information for three references to [email protected]. Best wishes, Reza Reza Khayat, PhD Assistant Professor The City College of New York Department of Chemistry, MR-1135 160 Convent Avenue New York, NY 10031 Tel. (212) 650-6070 www.khayatlab.org
