Hi, All CCP4BB Users, I have quite some data sets(~15) collected at different beam intensities, the individual dataset can diffract to ~3.8 A @I/dI=2. If I combine them, with AIMLESS in CCP4, the resolution can be extended to ~3A@I/dI=2. But, the Rmerge or Rpim is way high, in 10s or even 100s. Would this high R simply due to the intensity difference among these datasets? Or simply say, can I trust/use the combined/merged dataset diffracting to 3A?
Thanks! Charles -- *************************************************** Charles Chen Research Associate University of Pittsburgh School of Medicine Department of Anesthesiology ******************************************************
