Post doctoral position - Structural studies of full-length glutamate receptors
The Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences at the University of Copenhagen is offering a two-year post doctoral position within "Structural studies of full-length glutamate receptors" commencing 1 January 2015. Job description The position will be anchored at the Biostructural Research section, Department of Drug Design and Pharmacology, University of Copenhagen. The Biostructural Research section provides the foundation for structural and functional studies of a wide range of different proteins involved in health and disease. Ionotropic glutamate receptors (iGluRs) play a key role in fast excitatory synaptic transmission in the central nervous system. These receptors are critically important for normal brain function, such as learning and memory formation, whereas dysfunction in glutamatergic transmission has severe consequences on normal brain function, leading to disorders or diseases including Alzheimer’s disease and epilepsy. The aim of the research project is to explore conformational stages of iGluRs at the molecular level using primarily X-ray crystallography. Such information will facilitate structure-based drug design. The successful applicant is expected to teach up to 10% of her/his time in areas relevant to the research project. Qualifications required The successful applicant would be an experimentally skilled scientist who can document original scientific production in the areas of membrane protein expression using eukaryotic cells and subsequent purification for structural studies. Experience with expression of receptors in insect cells as well as X-ray crystallography is an advantage. Further information For further information, please contact Professor Jette S. Kastrup (j...@sund.ku.dk, tel. +45 3533 6486). Terms of employment The terms of employment and payment are according to the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. As an equal opportunities employer, the University of Copenhagen encourages all qualified applicants to apply, regardless of gender, age, religion and ethnic origin. Application Applications should include the following parts: 1) Application cover letter indicating motivation 2) Curriculum vitae 3) Copies of relevant diplomas 4) A complete list of publications indicating articles relevant to the position, including copies of these articles (max. 5) 5) Recommendation letters if relevant The parts must be clearly labeled with the above-mentioned numbers. Applications will not be taken into consideration, if the requirements listed above are not met. The application will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities. The University of Copenhagen encourages all interested in this position to apply. Please submit the application with the required attachments by clicking on "apply online" below. Only online applications will be accepted. The closing date for applications is 1st November 2014. Applications received after the deadline will not be considered. The Faculty of Health Sciences comprises app. 7500 students, app. 1500 PhD students and app. 3200 employees. The Faculty creates new knowledge and recognition through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the Faculty contributes to a healthy future through its graduates, research findings and inventions for the benefit of patients and the community. Apply online<http://jobportal.ku.dk/videnskabelige-stillinger/> The University of Copenhagen actively influences current and future generations through excellent research, education and co-operation. UCPH is one of the highest ranked universities in Europe and is Denmark´s oldest university, founded in 1479. Today, the University has 37,000 students and 9,000 employees affiliated across six faculties: humanities, law, natural sciences, social sciences, health sciences and theology. www.ku.dk/english/. Professor Jette Sandholm Kastrup Head of GluTarget (www.glutarget.ku.dk) Biostructural Research (www.farma.ku.dk/BR) Department of Drug Design and Pharmacology Faculty of Health and Medical Sciences University of Copenhagen Universitetsparken 2 DK-2100 Copenhagen Denmark Phone: +45 3533 6486 Email:j...@sund.ku.dk
