what about overlapping an ig domain with that disulphide in place with yours? then measuring the homologues cysteine separation? validity depends how close a match you get i suppose..
On 9 October 2014 08:42, Thomas Krey <[email protected]> wrote: > Dear all, > > I was wondering, if there is a tool out there that allows the easy > classification of immunoglobulin and Ig-like domain subclasses based on a > given pdb file. As far as I am aware the state-of-the-art for > immunoglobulin domains is to determine the distance (in amino acids) > between the two cysteines forming the canonical disulfide bond between > strands B and F. However, I am facing a couple of Ig-like domains that do > not contain this disulfide bond ! > Any help will be highly appreciated. > > Best regards > Thomas > > Dr. Thomas Krey > Institut Pasteur > Structural Virology Unit > 25-28 Rue du Docteur Roux > 75015 Paris > France > [email protected] >
