Dear Oarabile,

As Paul said, without any details it is hard to figure out what might be going 
on. Where did the cacodylate come from? Was it present in the starting pdb, did 
you create it yourself, or did you import it in Coot with the get monomer 
option? If you did not use the get monomer option, that would be the first 
thing to try. Delete the cacodylate present and use get monomer. That way you 
are sure that the nomenclature of the atoms is correct and that the cif file 
for cacodylate is loaded. Without cif file, the structure will explode, but in 
this case I would expect that Coot would not refine and produce an error 
message.

Best,
Herman



Von: CCP4 bulletin board [mailto:[email protected]] Im Auftrag von 
Kgosisejo, Oarabile
Gesendet: Samstag, 25. Oktober 2014 20:51
An: [email protected]
Betreff: [ccp4bb] Cacodylate won't stay in place

Hello all,

I am trying to fit cacodylate ion in my model using Coot but it does not stay 
where I put it. The molecule breaks apart and some of its components attach to 
the peptide residues. Due to this, phenix.refine would not accept this as the 
input for refinement. Is there a way I can make cacodylate ion stay in its 
electron density and refine my structure with cacodylate ion?

I appreciate your help!

Best Regards,

Oarabile M. Kgosisejo
[email protected]<mailto:[email protected]>

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