Postdoctoral Position in Structural Biology/Natural Product Biochemistry

The Helmholtz Centre for Infection Research and its branch Helmholtz Institute 
for Pharmaceutical Research (in Braunschweig and Saarbrücken, Germany) announce 
an opening for a postdoctoral research fellow in structural biology/natural 
product biochemistry. The position is associated with the departments 
“Microbial Natural Products” and “Structure and Function of Proteins”. 
Together, these groups work towards the discovery of novel anti-infectives.

The Helmholtz Centre for Infection Research and the Helmholtz Institute for 
Pharmaceutical Research:
Over 1000 people are employed at the Helmholtz Centre for Infection Research 
(HZI) and its branch institute, the Helmholtz Institute for Pharmaceutical 
Research Saarland (HIPS). Together, these institutions aim at developing new 
strategies against infectious disease within the health program of the 
Helmholtz Association of German Research Centers. One of our main activities is 
in the field of discovering new antibiotics from bacterial sources and 
investigating their mode of action and biosynthesis. The department “Microbial 
Natural Products” headed by Prof. Dr. Rolf Müller is internationally renowned 
for myxobacterial natural product research; the department “Structure and 
Function of Proteins” headed by Prof. Dr. Wulf Blankenfeldt works towards the 
elucidation and functional characterization of proteins involved in all aspects 
of infection biology. Both departments offer world-class equipment to pursue 
projects in natural product biochemistry within an environment that provides 
access to state-of-the-art facilities for infection research.

Projects:
The successful candidate will participate in joint projects of the departments 
“Microbial Natural Products” and “Structure and Function of Proteins”. He/she 
will be based at the Helmholtz Centre in Braunschweig to determine crystal 
structures of as well as biochemically and biophysically characterize proteins 
involved in the biosynthesis and interaction of antibiotically active natural 
products. The responsibilities will also include regular synchrotron data 
collection campaigns (PETRAIII, Hamburg; BESSYII, Berlin; SLS, 
Villigen/Swizerland; ESRF, Grenoble/France) and visits to the Helmholtz 
Institute in Saarbrücken.

Prerequisites:
Candidates should hold a Ph.D. in a life sciences related subject at the time 
of their employment. They should have a strong background in all aspects of 
macromolecular crystallography, including techniques of recombinant protein 
production and biophysical as well as biochemical characterization. Because of 
the collaborative nature of the planned projects, strong communication skills 
in English are a must.

Location:
Headquarter Braunschweig, occasionally Saarbrücken branch

Research Group:
Microbial Natural Products - Prof. Dr. Rolf Müller
Structure and Function of Proteins - Prof. Wulf Blankenfeldt

The Handicapped:
Qualified applicants with a disability will be given preference.

Starting date:
March 2015

Contract time limit:
3 years

Probation period:
6 months

Salary:
TVöD E13

Applications accepted until 31.12.2014

Candidates are asked to submit a full CV including a publication list, a cover 
letter outlining their interest in these positions, a brief summary of current 
and past research experience (max. 2 pages) and contact data of at least two 
referees. All documents and information should be provided in English or German.

Applications should refer to code 80/2014 and be sent by 15.12.2014 to:

Helmholtz Centre for Infection Research
Dept. of Human Resources
Inhoffenstraße 7
38124 Braunschweig
E-Mail: [email protected]

Information about the Institute and the group can be found on our website.


________________________________

Helmholtz-Zentrum für Infektionsforschung GmbH | Inhoffenstraße 7 | 38124 
Braunschweig | www.helmholtz-hzi.de
Das HZI ist seit 2007 zertifiziertes Mitglied im "audit berufundfamilie"

Vorsitzende des Aufsichtsrates: MinDir’in Bärbel Brumme-Bothe, 
Bundesministerium für Bildung und Forschung
Stellvertreter: MinDirig Rüdiger Eichel, Niedersächsisches Ministerium für 
Wissenschaft und Kultur
Geschäftsführung: Prof. Dr. Dirk Heinz; Franziska Broer
Gesellschaft mit beschränkter Haftung (GmbH)
Sitz der Gesellschaft: Braunschweig
Handelsregister: Amtsgericht Braunschweig, HRB 477

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