Hi Venu,

please send me PDB file and I will try to help.

FYI: There is Phenix mailing list for Phenix related questions.

Pavel


On Thu, Dec 11, 2014 at 1:07 PM, Venu V <[email protected]> wrote:
>
> Hello everybody,
> I need some help with handling modified DNA bases in phenix refinement.
> I am refining a duplex DNA structure (8 bases) that has a modified base
> (2nd base) . The modification is one of the Oxygen (at position 2) on a
> thymine is replaced by a Selenium. I used eLBOW of Phenix to create cif
> file for this modified base and then tried to connect this hetero base to
> the remaining bases. However I could not manage to get the refinement
> running.
> I was wondering if any body has an example of how to define the
> connections for DNA that has modified bases for phenix.refine.
> Thank you in advance.
> Sincerely
>  Venu
> ======
>

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