Hi Vaheh,

Thank you for point out this. You are right, the crystal is a plate and
somehow at certain angles the frames even failed index, I see a lot of
rejection spots when integration. From all the suggestions I got so far, I
think I have to grow better crystals and try better collecting data
strategies next time.

Xiao

On Tue, Jan 13, 2015 at 6:35 AM, Oganesyan, Vaheh <[email protected]>
wrote:

>  I might be completely wrong here but doesn’t it bother that the number
> of rejected reflections shown in log file is ~83000? It shows, at least to
> me, that either indexing step is far from being correct or crystal is not
> really good enough due to defects.
>
>
>
>
>
>
>
> *Vaheh Oganesyan*
>
> *www.medimmune.com <http://www.medimmune.com>*
>
>
>
> *From:* CCP4 bulletin board [mailto:[email protected]] *On Behalf Of *Xiao
> Lei
> *Sent:* Saturday, January 10, 2015 7:08 PM
> *To:* [email protected]
> *Subject:* Re: [ccp4bb] CCP4 Scalepack2mtz problem: Anisotropy correction
> failed
>
>
>
> Hi Eleanor,
>
>
>
> Thanks for the input, I attach the scale log file here.
>
>
>
> On Sat, Jan 10, 2015 at 2:16 PM, Eleanor Dodson <[email protected]>
> wrote:
>
> Certainly a negative eigen value is bad - can you attach the data? There
> may be some obvious problem..
>
> Eleanor
>
>
>
> On 10 January 2015 at 04:42, Xiao Lei <[email protected]> wrote:
>
> Dear All,
>
>
>
> I tried to convert my x-ray diffraction sca data from HKL200 (.sca file)
> to mtz in CCP4 using Scalepack2mtz and it failed, I do not know what should
> I supposed to do next to correct the problem, any suggestions are
> appreciated. I pasted the message from part of log file below:
>
>
>
>
> ANISOTROPY ANALYSIS (using intensities):
>
>
> Eigenvalues: -0.5668 0.1479 0.3584
>
> Eigenvalue ratios: -1.5815 0.4128 1.0000
>
> ctruncate: Anisotropy correction failed - negative eigenvalue.
>
> Times: User: 0.4s System: 0.0s Elapsed: 0:00
>
> ***************************************************************************
>
> * Information from CCP4Interface script
>
> ***************************************************************************
>
> The program run with command: /Applications/ccp4-6.4.0/bin/ctruncate
> -hklin "/LAB/CCP4/TEMP/RelADD_12212014ALS502_3_1_mtz.tmp" -hklout
> "/LAB/CCP4/TEMP/RelADD_12212014ALS502_3_3_mtz.tmp" -colin
> "/*/*/\[IMEAN,SIGIMEAN\]" -colout P1_12
>
> has failed with error message
>
> ctruncate: Anisotropy correction failed - negative eigenvalue.
>
> ObjectCache: Leaked 0005 refs to
>
> ***************************************************************************
>
>
>
> #CCP4I TERMINATION STATUS 0 " ctruncate:  Anisotropy correction failed -
> negative eigenvalue. ObjectCache: Leaked 0005 refs to
>
> "
>
> #CCP4I TERMINATION TIME 09 Jan 2015  19:55:50
>
> #CCP4I MESSAGE Task failed
>
>
>
>
>
>
>
>
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