Dear all, I am Deepa, MSc final year student. For my final year project, I am working on protein structure classification. I have a set of 300 methyltransferase protein structures. I wish to classify the proteins in to different groups based on their secondary structures and sequence. I have tried to classify the proteins based on sequence but it is not satisfactory in view point of structures. I have used the DALI server results like Z-score, RMS deviation for grouping. I ended up with 50-60 groups. I have used the PIRSF, but in that most of the structures are not available. I have also used Chimera - structure based sequence alignment, but the program is crashing for 300 structures. Any suggestions will be highly beneficial to me.
Thank you in advance. With regards Deepa
