*Post-doctoral position: Structure and function of a large membrane protein insertase complex*
A postdoctoral research position is available in the group of Sebastian Hiller at the Biozentrum, University Basel. In this project, we want to unravel the mechanism for insertion of beta-barrel membrane proteins into mitochondrial and bacterial outer membranes at atomic resolution. This process is mediated by large insertase complexes including Omp85 proteins. The project characterizes structure, function, and dynamics of such a complex using solution NMR spectroscopy and complementary techniques, in combination with suitable biochemical preparations. The project is ideally suited for a competitive researcher with experience in membrane protein biochemistry and solution NMR spectroscopy. Motivated individuals with a different background in structural biology are also strongly encouraged to apply. The Biozentrum offers an international and enthusiastic work environment with excellent infrastructure in all areas of life science. Our facilities for structural biology include 600-900 MHz Bruker NMR spectrometers, high-throughput crystallization screening, state-of-the-art cryo-electron microscopy, and a biophysics core facility. The position is available for a duration of at least two years and with a starting date within the next 6 months. Applicants should submit a CV, list of publications, a letter of motivation, and contact information for at least two reference persons. Prof. Sebastian Hiller Focal Area Structural Biology and Biophysics Biozentrum, University of Basel Klingelbergstrasse 70, 4056 Basel, Switzerland [email protected] http://www.biozentrum.unibas.ch/hiller/ phone: +41 61 267 20 82 fax: +41 61 267 21 09
