Dear colleagues,*
*
*At the VIB Structural Biology Research Center (Vrije Universiteit
Brussel / VIB), we are looking for a highly qualified and motivated
postdoctoral researcher with a strong background in X-ray
crystallography, biochemistry and biophysics and interested in
biochemical and structural studies on proteins and protein networks
involved in neuronal function and dysfunction. *
*Project description: *Epilepsy is a very common neurological disorder
for which currently available drugs are highly inefficient and
unspecific. *In collaboration with the group of Prof. Patrik Verstreken
(VIB Center for Brain & Disease Research), we are investigating novel
pathways leading to neurological disorders in general and epilepsy in
particular. The current project involves the detailed functional and
structural characterization of proteins and protein networks involved in
these epilepsy pathways, using *an approach of biochemical and
biophysical methods in combination with structural biology (For
background: Fischer et al Nat. Struct. Mol. Biol. 2016). This research,
combined with /in vivo/ studies, will contribute not only to a detailed
molecular mechanism on the involved proteins, but it will also pave the
way to establishing novel /in vivo /epilepsy models and device
strategies for medical intervention.
*Required skills and experience:***
*·**Ph.D. in structural biology*
*·**Experience in protein expression, purification and characterization*
*·**Experience in X-ray crystallography, biochemistry and biophysics*
*·**Experience with protein expression in mammalian systems is an asset *
*·**Good communication and teamwork skills*
*Contact:**Please send applications (including CV, research experience,
and at least two names and contact information for references)
to:**[email protected] <mailto:[email protected]>**.*
*About SBRC:**The VIB Structural Biology Research Center focuses on the
structure and dynamics of macromolecular complexes in health and
disease. Our multidisciplinary team of about 70 researchers is housed in
new laboratory facilities and combines extensive expertise in structural
biology (state of the art in-house X-ray crystallography, NMR, SAXS,
cryo-EM and atomic force microscopy), biophysics, enzymology and
molecular biology.*
Best regards,
Wim
--
Prof. Dr. ir. Wim Versées
Research group Structural Biology Brussels
Faculty of Science and Bioengineering Sciences
Vrije Universiteit Brussel
VIB Structural Biology Research Center
Building E, Room E4.2
Pleinlaan 2, 1050 Brussel
Belgium
Email: [email protected]
