Dear Nicolas,

are you sure this concept is correct?

The entropy of molecules arranged in a crystal must be greatly larger than in 
solution. Hence the driving force for crystallisation is actually a drop in 
energy, and I am not sure there is actually a barrier.

I would take the kids to the play ground and let them run around randomly. 
When I blow a wistle they should line up in an orderly manner.

I am sure it will take some time before some sort of order is achieved, for 
the kids could face in various directions, or line up in blocks, or other 
shapes. Once a seed is there, i.e. once e.g. 4-5 kids have created a regular 
block, it will be much easier for the rest to line up (this is consistent with 
Patrick's explanation).

Cheers,
Tim

On Wednesday 04 January 2017 05:45:50 PM Nicolas FOOS wrote:
> Dear Evette,
> 
> If I was is your situation (explaining nucleation and other concept). I
> will discuss in terms of energy.
> 
> I mean obtaining the initial nuclei is the "costly" step in terms of
> energy. To represent that, out the classical curve of energy, I will use
> a metaphoric representation such as jump over a barrier and run after.
> 
> With this analogy, it's possible to explain that the first step is
> difficult and the second more accessible. If the barrier is to high,
> it's impossible to continue and run. If you don't have any barrier it's
> easy to run and if you only have a small barrier is not to difficult to
> jump over and run. But It also allow you to explain that if you
> facilitate the apparition of the first "surface" thanks to appropriate
> method (seeding, dust...) you can help the first step (to continue with
> the barrier story, it like you have ladder to help, or the ability to
> decrease the size of the barrier.
> 
> For why the crystal and how, I will maybe use the example of orange
> pyramid in the food store. Orange are stable together because they have
> enough contact, because they have relatively homogeneous shape. If you
> mixed orange with water melon it's difficult to obtain nice pyramid.
> 
> For crystallization experiment which work, I have no Idea out of the one
> you already mentioned.
> 
> 
> Hope this help.
> 
> Nicolas
> 
> Nicolas Foos
> PhD
> Structural Biology Group
> European Synchrotron Radiation Facility (E.S.R.F)
> 71, avenue des Martyrs
> CS 40220
> 38043 GRENOBLE Cedex 9
> +33 (0)6 76 88 14 87
> +33 (0)4 76 88 45 19
> 
> On 30/12/2016 11:06, Radisky, Evette S., Ph.D. wrote:
> > Can anyone point to some especially useful resources to help explain
> > to kids (pre-chemistry, ~age 10-12) how and why molecules crystallize?
> > Maybe a good online movie or animation?  I am especially needing help
> > with the concept of nucleation, and why nucleation is slower and then
> > crystal growth faster once nuclei have formed.  I have been
> > supervising some experiments growing sucrose crystals from
> > supersaturated solutions, which have worked really well, but I am
> > having more difficulty in explaining the underlying fundamental
> > concepts in a way that is understandable to the kids.
> > 
> > Thanks!
> > Evette
> > 
> > Evette Radisky, PhD
> > 
> > Associate Professor of Cancer Biology
> > 
> > Mayo Clinic Cancer Center
> > 
> > Griffin Cancer Research Building
> > 
> > 4500 San Pablo Road <x-apple-data-detectors://3/0>
> > 
> > Jacksonville, FL 32224 <x-apple-data-detectors://3/0>
> > 
> > tel: 904-953-6372 <tel:904-953-6372>
> > 
> > fax: 904-953-0277 <tel:904-953-0277>
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