Remember that 2xADP can disproportionate into ATP + AMP
> On 19 Jan 2017, at 20:54, Panneerselvam, Saravanan > <[email protected]> wrote: > > Dear All, > Sorry for the little bit off topic. Is there a possibility for covalent > bond formation between beta phosphate of ADP and acetate molecule both > are coordinated by divalent metal ions? I am working on a Kinase > structure which was crystallized with ADP and in presence of 1M sodium > acetate. We observed additional density around ADP that fits perfectly > like a gamma phosphate , mimicking like ATP bound state, surrounded and > coordinated by two metal ions(resolution is 1.4A). There is a change in > space group (from I212121 to P212121 ) and further important > conformation changes are observed around ATP binding pocket and distant > region. This is the only xtal we obtained in this space group, and all > other xtals(measured 10 xtals) from the same plate belong to I212121. > > > > Thanks your help and time! > > Saravanan > ----- Original Message ----- > From: "CCP4BB automatic digest system" <[email protected]> > To: [email protected] > Sent: Sunday, 15 January, 2017 01:01:37 > Subject: CCP4BB Digest - 13 Jan 2017 to 14 Jan 2017 (#2017-15) > > There are 2 messages totaling 45 lines in this issue. > > Topics of the day: > > 1. Phenix (2) > > ---------------------------------------------------------------------- > > Date: Sat, 14 Jan 2017 20:58:09 +0000 > From: D Bonsor <[email protected]> > Subject: Phenix > > Is the phenix website down? Anyone know when it will be back up? > > ------------------------------ > > Date: Sat, 14 Jan 2017 14:45:06 -0800 > From: Pavel Afonine <[email protected]> > Subject: Re: Phenix > > See notice on Phenix mailing list that answers your question. > > On Sat, Jan 14, 2017 at 12:58 PM, D Bonsor <[email protected]> > wrote: > >> Is the phenix website down? Anyone know when it will be back up? >> > > ------------------------------ > > End of CCP4BB Digest - 13 Jan 2017 to 14 Jan 2017 (#2017-15) > ************************************************************
