Could you rename it for the time being - ASN or LEU for ASP or some such
cheat?
Not sure whether local NCS requires identical residue names as well as
conformations..
Eleanor

On 21 February 2017 at 10:39, Alice Dawson (Staff) <[email protected]>
wrote:

> Dear all
>
> I am working on a structure with 10 monomers in the asymmetric unit (2
> pentamers). I am using the NCSR local option in Refmac to automatically
> generate NCS restraints. This is working well (much better than the NCS
> restraints I defined manually). However there is one residue in one subunit
> that makes a hydrogen bond with an adjacent chain (due to crystal packing)
> and this pulls the side chain over by abut 0.3A. Sadly this is too small to
> cause these residues to be excluded automatically from the NCS restraints
> but large enough to make the difference map nasty. Is there any way to
> exclude residues from NCS local?
>
> Thanks (particularly as I have another 7 structures of the same protein to
> tidy up)
> Alice
>
> --
> Alice Dawson
> WNH Lab
> Division of Biological Chemistry and Drug Discovery
> School of Life Sciences
> University of Dundee
> 01382 385744
>
>
> The University of Dundee is a registered Scottish Charity, No: SC015096
>

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