Job-posting  - Seeking structural biologist with cryo-EM expertise at GSK

A vacancy for a structural biologist with cryo-EM expertise has opened up 
within the UK structural and biophysical sciences group at GlaxoSmithKline R&D. 
Joining an experienced multi-disciplinary group, this is an exciting 
opportunity for a motivated individual to complement and help shape our current 
capabilities in the EM area.
This is a permanent, full-time position suitable for a PhD degree holder (or 
equivalent).
To apply for this role and for further details, please click on the link below 
(Vacancy no : WD106591) 
https://careers.peopleclick.com/careerscp/client_gsk/external1931/gateway.do?functionName=viewFromLink&jobPostId=330903&localeCode=en-us
A full job description is also included at the end of this message.
Applications for this vacancy are to be made online by 24th MARCH
Informal inquiries can be sent to  
chun-wa.h.ch...@gsk.com<mailto:chun-wa.h.ch...@gsk.com>
Thank you for your interest,
Chun-wa Chung
UK Head Structural & Biophysics  Sciences
GlaxoSmithKline R&D
Stevenage
SG1 2NY
Tel no: +44 1438 763342
email : chun-wa.h.ch...@gsk.com<mailto:chun-wa.h.ch...@gsk.com>





Full Job Description (WD78277):

GlaxoSmithKline is a world leading research-based pharmaceutical company. We 
are focused around three core businesses: Pharmaceuticals, Vaccines and GSK 
Consumer Healthcare. We have a significant global presence with commercial 
operations in more than 150 countries, a network of 84 manufacturing sites in 
36 countries and large R&D centres in the UK, US,  Belgium and China.
The UK Structural and Biophysical Sciences group is a multi-disciplinary 
department within GSK R&D that provides molecular insights into drug discovery 
for both small molecule and biopharmaceutical programs.

We currently have an exciting opportunity for a laboratory-based scientist with 
expertise in state-of-the-art electron microscopy techniques to play an 
influential and key role in the application and development of these methods 
across small molecule and therapeutic protein programs. This individual will 
have extensive experience in the sample preparation and optimisation processes 
necessary to produce high-quality molecular images of protein structure, 
including direct experience of Cryo-EM methodologies. Experience of data 
analysis and interpretation is also expected. Being responsible for delivering 
structural insights to support program teams and contributing to the  wider 
protein structural and biophysical area by identifying and driving forward 
improvements and innovations that advance drug discovery projects, the 
individual must be a collaborative team player able to work successfully with 
other scientists within the department and within diverse teams.

Key Responsibilities and Accountabilities:
* Design and perform technical experiments in the EM area (sample preparation, 
optimisation and analysis).
* Document and communicate scientific results clearly and promptly.
* Provide strong scientific lead to shape EM strategy within structural biology 
and across therapeutic discovery programs.
* Build EM capabilities and infrastructure through interactions with the 
internal and external scientific community.
* Maintain scientific excellence and lead in a rapidly evolving area e.g. 
through interactions such as the FEI/LMB/Pharm consortium.
* Become an integral team member of multiple project teams.

Key Capabilities and Proficiency:
1. Technical expertise leading to Impact
Evidence of specific and in depth knowledge of transmission electron microscopy 
used as a structural technique, especially single particle cryo-EM. A track 
record of its application to address scientific problems relevant to 
pharmaceutical research.
2. Influence and Scientific awareness
Evidence of engagement with external scientific environment including the 
ability to identify and pursue opportunities that advance capabilities within 
own research area.
3. Team work
Demonstrable ability to both directly and indirectly influence and impact the 
progression of programs of research and to work in multi-disciplinary teams, 
displaying appropriate interpersonal skills and team work




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