Dear All,
We are working on a tetrameric protein containing 2 heterodimers which are related to each other by 2 fold symmetry. There are difference at the active site between the two heterodimers in the crystals, and we would like to make a difference map to compare one heterodimer to the other. I would really appreciate your advise and suggestions how to perform this comparison. Thank you, Oleg -- Oleg A. Zadvornyy, PhD Institute of Biological Chemistry, Washington State University 237 Clark Hall Pullman, WA 99163 Tel: (509)-335-9837 Lab: (509)-335-1958
