Dear Hugh
If you know Aggrescan then I assume you're away of its 3D counterpart?
http://biocomp.chem.uw.edu.pl/A3D/
It even allows you to consider whether structures reached by
coarse-grained MD are more aggregation-prone than your starting structure.
Good luck
Daniel
On 26/07/17 18:05, Hugh Morgan wrote:
Hi all, can anyone recommend a program for identifying hydrophobic
(aggregation) hotspots using either the amino acid sequence and/or structural
data.
Thanks in advance for your help
Hugh
Ps. Have tried aggrescan but would like to try a few others and compare,
ideally a more structural based program.
--
Dr Daniel John Rigden Tel:(+44) 151 795 4467
Institute of Integrative Biology FAX:(+44) 151 795 4406
Room 101, Biosciences Building
University of Liverpool http://pcwww.liverpool.ac.uk/~drigden/
Crown St.,
Liverpool L69 7ZB, U.K.
