Dear Raj, The pdb will accept any crystal structure submitted to them. They do not have editors and referees that refuse to accept crystal structures. In the worst case, your structure may have validation problems and you will get questions about it. But this will happen with published crystal structures as well.
There are online journals that will accept any paper (even fake ones) as long as the submission fee is paid. However, for “real” journals, it will depend on the information you get from your complex: does the buffer component bind in the active site? Could it be used as a kind of substrate/natural ligand analog to derive conclusions about the biological function of your protein? In that case you should include a minimum of biochemical data, showing that the buffer compound is a (competitive) inhibitor/activator of the protein, even if it is a very weak one. However, if your buffer component binds at some random place on the protein surface, or at some crystal contact, it may well be an artifact and it might be difficult to get such a structure published. Concerning the journal, look for journals that publish similar papers on similar proteins. There you have the best chance to get your paper accepted. Best, Herman Von: CCP4 bulletin board [mailto:[email protected]] Im Auftrag von raj kumar Gesendet: Montag, 29. Januar 2018 07:39 An: [email protected] Betreff: [EXTERNAL] [ccp4bb] Publishing structure of a protein Hi, We purified a protein whose structure (apo) is already known in pdb database and determined the crystal structure with a component of buffer. Can we submit this structure in pdb database and publish it as a research paper (only structure)? Also can anyone suggest some journals for this? Thanks Raj
