Dear all, Reminder for CCP-EM Spring Symposium. Similar to CCP4 Study Weekend this conference aims to provide a forum to highlight state of the art developments in computational cryoEM and related themes as well as showcasing outstanding recent applications. We promote an inclusive, friendly atmosphere welcoming both old and new to the community. Topics range from detector developments, image processing, single particle reconstruction, high resolution model building & validation, machine learning, tomography and electron diffraction.
The conference will be held 11-12th April at Keele University 2018 conference centre. Confirmed speakers include: Mark Basham (Diamond) SuRVoS: software for volume segmentation. https://diamondlightsource.github.io/SuRVoS/ Sacha de Carlo (Dectris) Detector technologies for high-resolution TEMs. Ana Casanal (MRC-LMB) Architecture of eukaryotic mRNA 3′-end processing machinery. http://science.sciencemag.org/content/358/6366/1056.full Peter Cherepanov (Crick Institute) A supramolecular assembly mediates lentiviral DNA integration. http://science.sciencemag.org/content/355/6320/93.long Paul Emsley (MRC-LMB) Coot model-building for cryoEM. https://www2.mrc-lmb.cam.ac.uk/personal/pemsley/coot/ Hans-Werner Fink (Zurich University) “Holography with Low-Energy Electrons: a Tool for Single Molecule Structural Biology.” http://www.pnas.org/content/114/7/1474 Achilleas Frangakis (Goethe University Frankfurt) “Image reconstruction and reliability algorithms for electron tomography.” Tim Gruene (Paul Scherrer Institut) "Collecting Diffraction Data with an Electron Microscope." Nicola Guerrini (STFC) Direct electron detector development at STFC from the Falcon and beyond. Ben Himes (Janelia) emClarity: software for sub-tomogram alignment and classification for hetrogeneous specimens. https://www.biorxiv.org/content/early/2017/12/08/231605 Arjen Jakobi (TU Delft) “Improving density interpretation by local sharpening of cryo-EM density maps.” https://git.embl.de/jakobi/LocScale https://elifesciences.org/articles/27131 Corinne Smith (University of Warwick) High resolution cryo-electron microscopy of clathrin cage networks. Carlos Oscar Sanchez Sorzano (CSIC Madrid) "Complex Image Processing Workflows and High resolution reconstructions using Scipion." http://scipion.i2pc.es/ Chris Russo (MRC-LMB) Ewald sphere correction using a single side-band image processing algorithm. https://www.sciencedirect.com/science/article/pii/S030439911730431X Charge accumulation in electron cryomicroscopy. https://www.sciencedirect.com/science/article/pii/S0304399117304291 Microscopic charge fluctuations cause minimal contrast loss in cryoEM. https://www.sciencedirect.com/science/article/pii/S0304399117304308 Beata Turonova (EMBL) Efficient 3D-CTF correction for cryo-electron tomography using NovaCTF improves subtomogram averaging resolution to 3.4 Å. https://doi.org/10.1016/j.jsb.2017.07.007 Giulia Zanetti (Birkbeck) Cryo-EM Structure of a Relaxase Reveals the Molecular Basis of DNA Unwinding during Bacterial Conjugation. http://www.cell.com/cell/abstract/S0092-8674(17)30423-3 Kai Zhang (MRC-LMB) Gctf: real-time CTF determination and correction. https://dx.doi.org/10.1016%2Fj.jsb.2015.11.003 Xiaodong Zhang (Imperial) Cryo-EM structures of the human INO80 chromatin-remodeling complex. doi:10.1038/s41594-017-0003-7 Registration site: http://www.cvent.com/d/9tq4ln Registration fees: PI/Industrial: £175.00 Student/PostDoc: £100.00 We have also ensured reasonably priced accomodation is available from Keele University (£70/room/night; available on registration). Best wishes, Tom, Helen, Colin & Martyn -- Dr Tom Burnley, PhD CCP-EM | @ccp_em <https://twitter.com/ccp_em>* | *www.ccpem.ac.uk Science and Technology Facilities Council (STFC) The Research Complex At Harwell Rutherford Appleton Laboratory, R92 OX11 0FA 01235 56 7871