Research Specialist/Cryo-Electron Microscopist
A Cryo-Electron Microscopist position is available in the Structural Biology 
Laboratory at
UT Southwestern Medical Center in Dallas, Texas. The person selected for this 
position will apply single particle cryo-electron microscopy to the study of 
protein structures.

Primary Responsibilities:
·      Work with other team members on sample grid preparation and grid 
·      Ensure high quality data acquisition on Talos Arctica and Titan Krios
·      Provide guidance in the use of current image processing programs and in 
structure determination and validation
·      Assist with final manuscript preparation

Required Education and Qualifications:
·      Ph.D. degree in biochemistry, biology, chemistry, physics or a related 
·      Expertise in the use of current cryo-electron microscopy methods
·      Good technical, communication, and teaching skills

Other Useful Skills:
·      Facility with related biophysical techniques such as cryo-EM tomography, 
X-ray crystallography, NMR, small-angle X-ray scattering, isothermal titration 
calorimetry, analytical ultracentrifugation and protein expression and 
purification is highly desirable.

UT Southwestern has recently established a new state-of-the-art cryo-electron 
microscopy facility housing a 200kV Talos Arctica for cryo-EM single particle 
screening and a 300kV Titan Krios for high-resolution structure determination. 
A sample grid lab is fully equipped with two Vitrobot robots, a Safematic HV 
Compact Coating Unit and assorted instruments for sample preparation. We are 
seeking a motivated individual to join a team of scientists in the Structural 
Biology Laboratory at UT Southwestern and participate in the research projects 
that utilize single particle cryo-electron microscopy technology for protein 
structure determination.

About the UT Southwestern Structural Biology Laboratory
The Structural Biology Laboratory (Diana Tomchick, Director) is a platform that 
allows researchers with different expertise to come together in a collaborative 
setting and tackle biological problems in a comprehensive way. Our publications 
are representative of the success of this strategy:
This position will be filled at the Research Specialist level with a salary 
commensurate with qualifications and experience.   The Research Specialist will 
be employed by the Howard Hughes Medical Institute (HHMI), which collaborates 
with UT Southwestern in conducting advanced biomedical research.
To Apply: please submit an application and provide a curriculum vitae, a brief 
statement of research and technical experience, and a list of three references 
at  HHMI is an Equal Opportunity Employer.  Women, 
minorities, veterans and individuals with disabilities are encouraged to apply.

For further inquiries, please contact:

Diana Tomchick, PhD
Director, Structural Biology Laboratory
Department of Biophysics, Rm. ND10.214A
UT Southwestern Medical Center
5323 Harry Hines Blvd
Dallas TX 75390-8816
Tel. +1 214 645 6383

Youxing Jiang, PhD
Professor of Physiology and Howard Hughes Medical Institute Investigator
Department of Physiology, Rm. ND13.300A
UT Southwestern Medical Center
5323 Harry Hines Blvd
Dallas TX 75390-
Tel. +1 214 645 6027
Diana R. Tomchick
Departments of Biophysics and Biochemistry
University of Texas Southwestern Medical Center
5323 Harry Hines Blvd.
Rm. ND10.214A
Dallas, TX 75390-8816
(214) 645-6383 (phone)
(214) 645-6353 (fax)


UT Southwestern

Medical Center

The future of medicine, today.

Reply via email to