Research Specialist/Cryo-Electron Microscopist A Cryo-Electron Microscopist position is available in the Structural Biology Laboratory at UT Southwestern Medical Center in Dallas, Texas. The person selected for this position will apply single particle cryo-electron microscopy to the study of protein structures.
Primary Responsibilities: · Work with other team members on sample grid preparation and grid screening · Ensure high quality data acquisition on Talos Arctica and Titan Krios · Provide guidance in the use of current image processing programs and in structure determination and validation · Assist with final manuscript preparation Required Education and Qualifications: · Ph.D. degree in biochemistry, biology, chemistry, physics or a related field · Expertise in the use of current cryo-electron microscopy methods · Good technical, communication, and teaching skills Other Useful Skills: · Facility with related biophysical techniques such as cryo-EM tomography, X-ray crystallography, NMR, small-angle X-ray scattering, isothermal titration calorimetry, analytical ultracentrifugation and protein expression and purification is highly desirable. UT Southwestern has recently established a new state-of-the-art cryo-electron microscopy facility housing a 200kV Talos Arctica for cryo-EM single particle screening and a 300kV Titan Krios for high-resolution structure determination. A sample grid lab is fully equipped with two Vitrobot robots, a Safematic HV Compact Coating Unit and assorted instruments for sample preparation. We are seeking a motivated individual to join a team of scientists in the Structural Biology Laboratory at UT Southwestern and participate in the research projects that utilize single particle cryo-electron microscopy technology for protein structure determination. About the UT Southwestern Structural Biology Laboratory The Structural Biology Laboratory (Diana Tomchick, Director) is a platform that allows researchers with different expertise to come together in a collaborative setting and tackle biological problems in a comprehensive way. Our publications are representative of the success of this strategy: http://www3.utsouthwestern.edu/sbl/Publications.html This position will be filled at the Research Specialist level with a salary commensurate with qualifications and experience. The Research Specialist will be employed by the Howard Hughes Medical Institute (HHMI), which collaborates with UT Southwestern in conducting advanced biomedical research. To Apply: please submit an application and provide a curriculum vitae, a brief statement of research and technical experience, and a list of three references at www.hhmi.org/Careers. HHMI is an Equal Opportunity Employer. Women, minorities, veterans and individuals with disabilities are encouraged to apply. For further inquiries, please contact: Diana Tomchick, PhD Director, Structural Biology Laboratory Department of Biophysics, Rm. ND10.214A UT Southwestern Medical Center 5323 Harry Hines Blvd Dallas TX 75390-8816 Tel. +1 214 645 6383 Email: diana.tomch...@utsouthwestern.edu<mailto:diana.tomch...@utsouthwestern.edu> Youxing Jiang, PhD Professor of Physiology and Howard Hughes Medical Institute Investigator Department of Physiology, Rm. ND13.300A UT Southwestern Medical Center 5323 Harry Hines Blvd Dallas TX 75390- Tel. +1 214 645 6027 Email: youxing.ji...@utsouthwestern.edu ************************************************** Diana R. Tomchick Professor Departments of Biophysics and Biochemistry University of Texas Southwestern Medical Center 5323 Harry Hines Blvd. Rm. ND10.214A Dallas, TX 75390-8816 diana.tomch...@utsouthwestern.edu (214) 645-6383 (phone) (214) 645-6353 (fax) ________________________________ UT Southwestern Medical Center The future of medicine, today.