The World's Brightest Minds Always Innovate
At St. Jude Children's Research Hospital, we know what can be achieved when the 
brightest scientific minds face the fewest barriers. That's why we provide 
world-class facilities. State-of-the-art technologies. Extraordinary support. 
And a collaborative, bench-to-bedside environment where you can see, firsthand, 
how your science translates into survival for the children we serve. Quite 
simply, at St. Jude, we encourage you to dream big, and we give you everything 
you need to be the force behind our cures.

Cryo-EM Specialist
Memphis, TN

Overview
St. Jude is setting up a new, state-of-the-art cryoEM facility that will house 
a 300kV Titan Krios and a 200 kV Talos Arctica electron microscope, both 
equipped with a K3 direct electron detector and energy filter, for high 
resolution structural studies of biological molecules as well as a 120kV 
instrument for routine electron microscopy applications.  The cryoEM facility 
will be supported by the newly established St. Jude Data Center, which houses a 
6,400-core high performance computing facility.
We are seeking a highly motivated individual to join the team as a cryoEM 
scientist to support the mission of the facility in high resolution cryoEM. The 
successful candidate will be responsible for operating and maintaining those 
electron microscopes on the daily basis, training and assisting users, 
participating in development of cryoEM technology, and performing other duties 
as assigned.  Salary will be competitive and will be commensurate with 
experience of the candidate.
Responsibilities

*         Daily operation and maintenance of electron microscopes, serving as 
an interface to the electron microscope manufacture's engineers to ensure 
optimal performance of the instruments;

*         Operation and maintenance of cryoEM-related ancillary equipment such 
as Vitrobot, carbon coater, plasma cleaner, etc.

*         Sample preparation with FEI Vitrobot and manual plunger-freezer;

*         CryoEM image collection;

*         Training, assisting and overseeing users in sample preparation and 
data collection;

*         Managing the cryoEM facility, including, but not limited to 
organizing the labs, ordering supplies, keeping records, writing reports, and 
other activities as assigned;

*         Developing and implementing efficient strategies for sample 
preparation and data collection;

*         Participating in development and implementation of new 
methods/techniques in cryoEM;
Minimum Experience

*         A minimum of 2-5 years of experience in cryoEM analysis of biological 
molecules;

*         Hands-on experience in operation of electron microscopes for image 
collection;

*         Hands-on experience in operation of Vitrobot, manual plunger and/or 
other related equipment in biological electron microscopy;

*         Experience in high resolution cryoEM;

*         Hands-on experience in usage of cryoEM software such as Leginon for 
automated image collection;

*         Hands-on experience in operation of Titan Krios and Talos Arctica;

*         Experience in cryo electron tomography a plus;

*         Skills in working and communicating with scientists at all levels;

*         Ability in working on multiple challenging tasks in a rapidly-paced 
environment.

*         A strong publication record;
Minimum Education

*         A PhD in biochemistry, biophysics, structural biology or a related 
field
Ready to join a team that is always innovating, because we believe anything is 
possible?
Apply now at: 
https://bit.ly/2I8jyRU<https://na01.safelinks.protection.outlook.com/?url=https%3A%2F%2Fbit.ly%2F2I8jyRU&data=01%7C01%7CCaryn.Cloer%40stjude.org%7C3ecb27c85e9245c874fc08d5b782234b%7C22340fa892264871b677d3b3e377af72%7C0&sdata=3TPVA%2BMeEtk72oZXAHcVT%2FIuh%2FiGtkQPnzc9xquVMAs%3D&reserved=0>

St. Jude Children's Research Hospital is an Equal Opportunity Employer. St. 
Jude does not discriminate on the basis of race, national origin, sex, genetic 
information, age, religion, disability, sexual orientation, gender identity, 
transgender status, veteran's status or disabled veteran's status with respect 
to employment opportunities.  All qualified applicants will be considered for 
employment.  St. Jude engages in affirmative action to increase employment 
opportunities for minorities, women, veterans and individuals with disabilities.


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