DearAll,

Afully-funded Postdoc position is available in the Pasteur Institute, in 
Paris.Our goal is to study the structure and function of a new class of 
DNApolymerases involved in DNA replication, and decipher the molecular 
mechanismsthey evolved to efficiently replicate DNA in molecular machines 
(replisomes).This integrated structural study will use primarily Cryo-EM 
approaches.

TheUnit for Structural Dynamics of Macromolecules at the Pasteur Institute is 
awell published and highly dynamic research environment that applies 
amultidisciplinary research strategy including structural biology, 
biochemistry,and biophysics to address fundamental questions about the 
molecular mechanismsof DNA replication. The laboratory is situated at the 
Pasteur Institute inParis that has an outstanding range of facilities and 
instrumentation,including a state-of-the-art Titan Kryos equipped with a K3 
camera, a F20(200kV) microscope equipped with a Falcon 2 camera, and two T12 
(120 kV)microscopes. Additional resources for specimen preparation and image 
processingare in place. 

Applicantsshould hold a PhD in the area of structural biology, biochemistry, or 
molecularbiology. Experience in cryo-electron microscopy, and data processing 
would be aplus, but not an absolute pre-requisite.

 

Pleasecontact me with informal inquiries about the position 
([email protected]) 

 

Dr.Ludovic Sauguet

InstitutPasteur

Departmentof Structural Biology & Chemistry

25 rue du Docteur Roux

75015 Paris

France

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