It seems that your CoA is one carbon out of reference. You have spotty
difference density over the ligand. Shift it left by one carbon bond and
redune to see if density fits better.

Artem

On Wed, Jul 4, 2018, 02:26 张士军 <21620150150...@stu.xmu.edu.cn> wrote:

> Hi all
>
> I got a structure which has COA in it, and the SH in the tail of COA
> is very close to the SH side chain of Cys in the structure. I don't know
> whether it is disulfate bond or not? I remember they should link together if 
> they are disulfate bond,am I right? so what could this be? Thanks a lot!!!
>
>
> best regards
>
> shijun
>
>
>
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