Postdoctoral position investigating the impact of genetic variations on 
three-dimensional structure/function of proteins available in the laboratory of 
Jamaine Davis at Meharry Medical College in Nashville, TN



There is an immediate availability in the laboratory of Jamaine Davis for an 
enthusiastic postdoc who is interested in the molecular recognition of protein 
complexes essential for genome maintenance. The successful candidate will 
investigate DNA repair protein structure and complex assembly mechanisms using 
X-ray crystallography and/or single-particle cryo-EM, in addition to performing 
functional assays. The work in the lab is generally geared towards developing a 
mechanistic understanding of the DNA damage response using functional and 
structural techniques. The ideal candidate for this position is a protein 
biochemist who has experience in X-ray crystallography and wants to gain 
experience in cryo-EM.



We are located on the campus of Meharry Medical College within vibrant 
Nashville, aka Music City. Nashville has been rated #12 on Forbes list of best 
places for businesses and careers. Our lab is also a member of the Center for 
Structural Biology at Vanderbilt University 
(http://structbio.vanderbilt.edu/faculty/davis.php),where we have access to the 
Vanderbilt Cryo Electron Microscopy Facility (V-CEM). The V-CEM facility houses 
high-resolution transmission electron microscopes (TEMs) and cameras needed to 
collect data for single particle analysis and tomography.



Qualifications and experience: Candidates should hold a Ph.D. in a relevant 
field and have a solid background in protein biochemistry. Candidates with 
prior experience in protein expression/purification, mutagenesis, structure 
determination (e.g., X-ray, NMR) and protein-nucleic acid interaction are 
preferred.  Experience with cryo-EM is advantageous. Excellent verbal and 
written English communication skills, and ability to work in close 
collaboration with other researchers are required.



Qualified applicants should send a cover letter, CV, and the names of three 
references by email to Jamaine Davis at [email protected]<mailto:[email protected]>.



Jamaine S. Davis, Ph.D. | Assistant Professor
Department of Biochemistry & Cancer Biology | School of Medicine
Meharry Medical College | 1023 21st Avenue N | 2007 WBS Bldg | Nashville, TN 
37208
Of: 615-963-2847 | Lab: 615-327-6383
[email protected]<mailto:[email protected]>

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