Hi,

Please note that for polder maps, the bulk solvent is reset locally.
Turning bulk solvent off entirely most likely deteriorates maps.

Best wishes,

Dorothee

On Mon, Feb 4, 2019 at 3:50 AM Samuel Davis (PG Research) <
[email protected]> wrote:

> Hi,
>
> I'm wondering if anyone knows if it is possible to turn off the bulk
> solvent modelling in Refmac5, for the purpose of generating Polder maps? I
> know that an option for Polder maps is directly implemented in Phenix, but
> we ideally want to use Refmac5, as we have used it for the rest of our
> refinement and want to keep it consistent if possible.
>
> Thanks,
>
> Samuel.
>
> Samuel Davis
> MRC 3.5 Year Programme PhD Student
> Life Sciences, Biological Chemistry and Drug Discovery, University of
> Dundee
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>
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