Try seeding at lower concentration.

From: CCP4 bulletin board <[email protected]> On Behalf Of zhangyi19950109
Sent: Friday, March 22, 2019 1:55 AM
To: [email protected]
Subject: [ccp4bb] image

Dear all,
A single plus-stranded RNA virus RDRP monomer grows crystals, precipitants 
(PEG8000)
with low concentration, more nucleuses and poor resolution.Reduce precipitant 
concentration can reduce the crystal nucleus, but worse resolution, precipitant 
concentration increased, many crystal nucleus and crystal is very small.  Try 
to optimize the temperature, pH, protein concentration, dehydration, additives, 
detergent, sit and hanging drop, but were not improved much.  Pease provide 
some advice methods.
This is a picture of this crystal
[cid:[email protected]]




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