The Lee Lab in the Department of Pharmacology, at the Yale School of Medicine, has an immediate opening for a highly motivated Postdoctoral Associate to investigate the molecular mechanism of endocrine fibroblast growth factor (FGF) signaling. Endocrine FGFs, which include, FGF15/19, FGF21, and FGF23, activate signaling via FGF receptors and require binding to the Klotho family of surface receptors; FGF23 signaling requires alpha-Klotho, while FGF15/19 and FGF21 signaling requires beta-Klotho. The research in our laboratory is focused on the structural elucidation, biophysical, and biochemical analyses of complexes involved in endocrine FGF signaling.
Applicants should have a PhD in biochemistry, biophysics, or a related field and should have extensive experience in recombinant protein production (E.coli and mammalian cells) and structural biology techniques (X-ray crystallography or cryo-EM), as well as excellent written and oral communication skills. Experience with mammalian cell culture and quantitative biophysical analyses are also desirable. Interested candidates should send a current CV, a statement of research interests, and the names and contact information of three references to Sangwon Lee (s....@yale.edu). Yale University is an Affirmative Action/Equal Opportunity Employer and welcomes applications from women, members of minority groups, persons with disabilities and protected veterans. ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
