Hey Zac A good scan of page 228 in Georgina Ferry’s biography of Max Perutx (Max Perutz and the secret of life) will do the trick. It is a 18x13 cm photo. I have it in front of me!
best Savvas > On 10 Apr 2019, at 16:29, Zachary A. Wood <z...@uga.edu> wrote: > > Hello Fellow Structural Enthusiasts, > > My apologies for the slightly off-topic question. I am trying to track down a > higher resolution image of the jpg that I have attached. I use this photo of > Max Perutz when I am teaching about protein folding, and have always wanted a > better quality one. I believe it is credited to Nature, and I am trying to > find out what issue, but I am hoping that one of you may have more > information or perhaps even a better photo. Thanks for any help, and for > those of you who may never have seen this photo before, I hope you enjoy it. > I like to imagine that Perutz is considering the challenges associated with > folding that chain after he determined the crystal structure. If you have > never read the discussion in his famous Nature paper, I will leave you with a > relevant quote of him referring to the structural similarity between horse > hemoglobin and sperm whale myoglobin, in which he predicts the thermodynamic > hypothesis (Anfinsen’s dogma): > > “How does this arise? It is scarcely conceivable that a three-dimensional > template forces the chain to take up this fold. More probably, the chain, > once synthesized and provided with a haem group around which it can coil, > takes up this configuration spontaneously, as the only one which satisfies > the stereochemical requirements of its amino acid sequence.” > > Thank you for any help you may be able to offer! > > Best regards, > > Z > > *********************************************** > Zachary A. Wood, Ph.D. > Associate Professor and Graduate Coordinator > Department of Biochemistry & Molecular Biology > University of Georgia > Life Sciences Building, Rm A426B > 120 Green Street > Athens, GA 30602-7229 > Office: 706-583-0304 > Lab: 706-583-0303 > FAX: 706-542-1738 > *********************************************** > <perutz-nature.jpg> > > To unsubscribe from the CCP4BB list, click the following link: > https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1 > <https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1> ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
