Hi,

A newly funded Wellcome Investigator Award in Science entitled, “Dynamic 
Structural Biology: New Tools and Strategies for General Applications” has 
positions for up to four post-doctoral research associates (PDRAs). The 
principal science drivers include (metallo)enzymes that either make or degrade 
antibiotics. These include, but are not limited to, isopenicillin N synthase 
and a broad range of beta-lactamases.  We conduct research and development at 
the forefront of serial and time-resolved macromolecular crystallography. We 
also work to transfer those techniques that are complementary and synergistic 
between XFELs, synchrotrons and cryo-EM. Our research and development efforts 
cross several fronts in biophysics from enzyme kinetics to various types of 
spectroscopy and includes a variety of serial crystallography experiments at 
Diamond Light Source and at several XFEL facilities around the world. We are 
seeking scientists interested in time-resolved structural biology and/or with 
experience in serial femtosecond crystallography or spectroscopy at XFEL 
sources.

For more information please contact me. For details and how to apply please 
follow these links:
https://www.diamond.ac.uk/Careers/Vacancies.html

Biophysics (Job ID 10149) with an emphasis on enzymes reaction mechanisms.
https://vacancies.diamond.ac.uk/vacancy/post-doctoral-research-associate-pdra-xfel-hub-biophysics-377881.html

Computational (Job ID 10187) with an emphasis on serial crystallography data 
processing and/or molecular dynamics simulations.
https://vacancies.diamond.ac.uk/vacancy/post-doctoral-research-associate-pdra-xfel-hub-computation-384334.html

Instrumentation / engineering (Job ID 10188) with an emphasis on serial 
crystallography correlated with X-ray emission spectroscopy collected at 
storage rings and/or at XFELs.
https://vacancies.diamond.ac.uk/vacancy/post-doctoral-research-associate-pdra-xfel-hub-instrumentation-384336.html

Sincerely,

AMO
~ ~ ~ ~ ~
Allen M. Orville, Ph.D.
Wellcome Investigator and Royal Society Wolfson Fellow
Principal Scientist, XFEL Hub at Diamond Light Source
Harwell Science and Innovation Campus
Didcot, Oxfordshire
OX11 0DE
United Kingdom
e-mail: [email protected]<mailto:[email protected]>
AMO site: https://www.diamond.ac.uk/Instruments/Mx/XFEL-Hub/Staff/Orville.html
XFEL-Hub site: https://www.diamond.ac.uk/Instruments/Mx/XFEL-Hub.html



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