Hi Ivan,
> My conclusion is that "no fill-in" option might be tried at some > stages, but with caution, especially for datasets with poor low res > completeness. > I'm guessing you really meant *high*, not low. More or less repeating what others said already.. Correcting for low res completeness doesn't add high-res details and so has lesser risk of introducing model bias at atomic level. Contrary, filling in high-res terms is likely to noticeably bias the map at atomic level of detail. Here is one of my favorite examples of what missing low-res data can do to your map: http://cci.lbl.gov/~afonine/tmp/1nh2.pdf Pavel ######################################################################## To unsubscribe from the CCP4BB list, click the following link: https://www.jiscmail.ac.uk/cgi-bin/webadmin?SUBED1=CCP4BB&A=1
